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         (1)  the   report  of  the   National  Academy  of  Sciences

      authorized by section 112(o)  of the Clean Air Act, the use and

      limitations  of  risk assessment  in  establishing  emission or

      effluent  standards,  ambient  standards,  exposure  standards,

      acceptable   concentration   levels,   tolerances    or   other

      environmental criteria for hazardous  substances that present a

      risk of  carcinogenic effects  or other chronic  health effects

      and the suitability of risk assessment for such purposes;

         (2)   the  most   appropriate  methods  for   measuring  and

      describing  cancer  risks  or  risks of  other  chronic  health

      effects from  exposure to hazardous substances considering such

      alternative approaches as the lifetime  risk of cancer or other

      effects  to  the  individual  or individuals  most  exposed  to

      emissions from a source or sources  on both an actual and worst

      case basis, the range of such risks, the total number of health

      effects avoided  by  exposure reductions,  effluent  standards,

      ambient    standards,     exposures    standards,    acceptable

      concentration  levels,  tolerances   and  other   environmental

      criteria,  reductions  in  the  number of  persons  exposed  at

      various  levels of  risk, the  incidence  of cancer,  and other

      public health factors;

         (3)  methods  to reflect  uncertainties  in  measurement and

      estimation   techniques,  the   existence  of   synergistic  or

      antagonistic effects  among hazardous substances,  the accuracy

      of extrapolat-

      ing  human  health risks  from  animal exposure  data,  and the

      existence of  unquantified direct or indirect  effects on human

      health in risk assessment studies;

         (4)  risk  management policy  issues  including  the  use of

      lifetime cancer risks to individuals most exposed, incidence of

      cancer,   the  cost  and   technical  feasibility  of  exposure

      reduction measures and the use of site-specific actual exposure

      information   in   setting   emissions  standards   and   other

      limitations  applicable to  sources  of  exposure to  hazardous

      substances; and

         (5) and comment on  the degree  to which it  is possible  or

      desirable to  develop a consistent risk assessment methodology,

      or  a consistent  standard  of acceptable  risk, among  various

      Federal programs.

   (c) Membership.-Such Commission  shall be composed of  ten members

who shall have knowledge or experience in fields of risk assessment or

risk  management,  including  three members  to  be  appointed  by the

President, two  members to be appointed by the Speaker of the House of

Representatives,  one member to be appointed by the Minority Leader of

the  House  of Representatives,  two members  to  be appointed  by the

Majority  Leader of  the Senate,  one member  to be  appointed by  the

Minority  Leader of the Senate, and one  member to be appointed by the

President  of the National Academy of Sciences.  Appointments shall be

made not later than 18 months after the date of enactment of the Clean

Air Act Amendments of 1990.  

   (d)   Assistance   from   Agencies.-The   Administrator   of   the

Environmental   Protection  Agency   and  the   heads  of   all  other

departments, agencies,  and instrumentalities of the  executive branch

of the  Federal Government shall,  to the maximum  extent practicable,

assist  the Commission in gathering such information as the Commission

deems  necessary to carry out this section subject to other provisions

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