X hits on this document

204 views

0 shares

0 downloads

0 comments

42 / 68

1/26/2015

42

AML – Subtype M3

Acute promyelocytic leukemia

May be one of two types, hypergranular or microgranular

Stain strongly positive with myeloperoxidase

M3 patients must be recognized because bleeding problems (DIC) occur when these patients are treated and the granules are released

Make up approximately 15% of all AML cases

Treatment with all-trans retinoic acid (ATRA) a form of Vitamin A causes the cells to undergo maturation (cells have a defective vitamin A receptor)

Document info
Document views204
Page views200
Page last viewedMon Jan 16 22:22:39 UTC 2017
Pages68
Paragraphs665
Words3179

Comments