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Case Report: Blastic Natural Killer (NK) Cell Leukemia (Agranular CD4+CD56+ Leukemia) - page 2 / 4

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Blastic NK leukemia

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Fig. 1. Panel A: In the blood smear, the leukemic cells show relatively dispersed nuclear chromatin and nucleoli and no cytoplasmic azurophilic granules. Panels B and C show the leukemic cells diffusely infiltrating the bone marrow.

Fig. 2. Immunophenotyping of the leukemic cells: CD45+ low, CD56+ bright, CD4+ bright, HLA-Dr+, CD43+, CD38+ CD68+; and CD3-, cCD3-, CD2-, CD5-, CD8-, CD7-, CD1a-, cCD79a-, CD19-, CD20-, FMC-7-, CD24-, CD11c-, kappa-, lambda-, CD34-, TdT-, CD10-, CD30-, CD16-, and CD57-. CD13-, CD33-, CD11b-, CD15-, CD14-, and CD64- (data not shown).

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