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if the duration of insulin action is determined to be inadequate. If twice daily treatment is initiated, the two doses should be 25% less than the once daily dose required to attain an acceptable nadir. For example, if a dog receiving 20 units of VETSULIN once daily has an acceptable nadir but inadequate duration of activity, the VETSULIN dose should be changed to 15 units twice daily.

Further adjustments in dosage may be necessary with changes in the dog’s diet, body weight, or concomitant medication, or if the dog develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.

CATS

The initial recommended dose in cats is 1 to 2 IU per injection. The injections should be given twice daily at approximately 12 hour intervals. For cats fed twice daily, the injections should be given concurrently with, or right after each meal. For cats fed ad libitum, no change in feeding schedule is needed. The veterinarian should re- evaluate the cat at appropriate intervals and adjust the dose based on clinical signs, urinalysis results, and glucose curve values until adequate glycemic control has been attained.

Further adjustments in dosage may be necessary with changes in the cat’s diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.

K. Route(s) of Administration:

VETSULIN should be administered subcutaneously using a U-40 insulin syringe and should be given 2 to 5 cm (3/4 to 2 in) from the dorsal midline, varying from behind the scapulae to the mid-lumbar region and alternating sides.

L. Species/Class(es):

Dogs and Cats

M. Indication(s):

VETSULIN (porcine insulin zinc suspension) is

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