X hits on this document

PDF document

Key Words: diabetes mellitus  metabolic syndrome  epidemiology  obesity  risk factors  ... - page 7 / 11

23 views

0 shares

0 downloads

0 comments

7 / 11

486

Circulation

July 31, 2007

Incident, n

No. at Risk*

Age- and Sex-Adjusted OR (95% CI)

Multivariable-Adjusted OR (95% CI)

327 130 91 221

4665 1420 853 2273

Referent 1.29 (1.04 to 1.60) 1.51 (1.18 to 1.94) 1.37 (1.14 to 1.65)

Referent 1.21 (0.90 to 1.62) 1.50 (1.06 to 2.11) 1.31 (1.02 to 1.68)

840 281 181 462

3665 1113 645 1758

Referent 1.29 (1.10 to 1.51) 1.55 (1.28 to 1.88) 1.38 (1.20 to 1.58)

Referent 1.25 (1.02 to 1.54) 1.40 (1.08 to 1.83) 1.30 (1.09 to 1.56)

898 322 206 528

4264 1359 836 2195

Referent 1.20 (1.03 to 1.39) 1.28 (1.07 to 1.53) 1.23 (1.08 to 1.39)

Referent 1.21 (0.99 to 1.47) 1.32 (1.03 to 1.69) 1.25 (1.05 to 1.48)

631 232 141 373

3055 1043 654 1697

Referent 1.23 (1.03 to 1.46) 1.20 (0.97 to 1.49) 1.22 (1.05 to 1.41)

Referent 1.16 (0.92 to 1.47) 1.20 (0.90 to 1.60) 1.18 (0.96 to 1.44)

695 250 148 398

4258 1317 807 2124

Referent 1.24 (1.05 to 1.46) 1.20 (0.98 to 1.46) 1.22 (1.07 to 1.41)

Referent 1.35 (1.09 to 1.67) 1.09 (0.82 to 1.44) 1.25 (1.04 to 1.51)

460 183 96 279

3878 1201 684 1885

Referent 1.28 (1.06 to 1.54) 1.13 (0.89 to 1.43) 1.22 (1.04 to 1.44)

Referent 1.38 (1.08 to 1.77) 1.21 (0.87 to 1.68) 1.32 (1.06 to 1.64)

TABLE 4. Multiple Logistic Regression Analysis Examining the Relations of Incidence of Individual Components of Metabolic Syndrome According to Soft Drink Consumption (Data From All 3 Examinations 4, 5, and 6)

Sample sizes for multivariable models in each category differed from age-adjusted models for obesity (n4277), waist circumference (n3321), impaired fasting glucose (n3858), high blood pressure (n2803), high triglycerides (n3792), and low HDL-C (n3501). OR indicates odds ratio; CI, confidence interval. *Participants without the individual component at baseline were eligible. No. of people represents person-observations.

  • Multivariable models adjust for baseline level of the metabolic syndrome component and age, sex, physical activity index, smoking, dietary consumption of

saturated fat, trans fat, fiber, magnesium, total calories, and glycemic index.

Soft Drink Consumption, Servings/d

Incidence of obesity (BMI 30 kg/m2) None 1

  • 2

  • 1

Incidence of increased waist circumference (102 cm for men and 88 cm for women)

None 1

  • 2

  • 1

Incidence of impaired fasting glucose (5.5 mmol/L o diabetes)

None 1

  • 2

  • 1

Incidence of high blood pressure (135/85 mm Hg or on treatment)

None 1

  • 2

  • 1

Incidence of hypertriglyceridemia (1.7 mmol/L or on treatment)

None 1

  • 2

  • 1

Incidence of low HDL-C (1.03 mmol/L for men or

  • 1.3 mmol/L for women or on treatment)

None 1

  • 2

  • 1

r

Strengths and Limitations The strengths of the present study include the large community-based sample of men and women and the adjust- ments for potential confounders; however, several limitations merit comment. We chose to use the modified definition of metabolic syndrome recommended by the National Choles- terol Education Program14 and did not use other criteria for the syndrome (such as those suggested by the World Health soft drink consumption with the risk of developing meta- bolic syndrome and its component traits. It is conceivable, though, that there may be residual confounding caused by lifestyle factors not adjusted for in the present analyses. Last, it has been suggested that the obesity-promoting effects of soft drinks may be related in part to their costs, with less expensive drinks being associated with greater hazard by virtue of their preferential selection for eco- nomic reasons.13 The present investigation could not ex- plore this explanation. or the European panel). Researchers have Organization41 Given the found high correlation between these guidelines.42 Downloaded from http://circ.ahajournals.org/ by guest on February 4, 2015

Document info
Document views23
Page views23
Page last viewedFri Dec 02 21:06:41 UTC 2016
Pages11
Paragraphs535
Words7772

Comments