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22,864 11,720 16,701 16,110 9,523 11,705 7,642 1,944 19,237 6,934 23,251 22,874 2,410 17,793 2,101

551,022 33,988 197,907 58,801 121,323 126,531 152,687 60,711 849,314 174,251 356,438 788,009 112,185 273,656 39,163

3,386 43,845 4,033 3,888 44,364

129,921 70,590 251,216 84,486 487,560

18,918 18,050 1,396 9,362 7,800

137,912 127,974 27,920 113,093 32,760

29,339 4,610 13,383 14,764 3,853 6,915 40,720 20,686 4,093 2,460 13,769 2,700 38,344 22,483 12,162 3,693 2,845 31,252

43,422 30,057 56,476 219,098 102,297 46,400 188,126 683,672 38,924 57,318 44,612 114,237 338,961 138,945 101,553 57,685 26,089 302,519

34,539 7,177 13,460 4,262 4,321 4,517 12,196 3,005 3,008 2,675 6,221 4,080 16,634 13,135 7,915 12,877 2,250

64,933 209,425 58,013 96,108 112,951 298,122 140,864 128,013 20,424 21,507 141,777 47,899 60,381 200,571 235,788 104,690 33,008

Idenix Pharmaceuticals, Inc.* Idera Pharmaceuticals, Inc.* ImmunoGen, Inc.* (a) Immunomedics, Inc.* (a) Infinity Pharmaceuticals, Inc.* Inovio Pharmaceuticals, Inc.* Insmed, Inc.* Insys Therapeutics, Inc.* (a) InterMune, Inc.* (a) Intrexon Corp.* (a) Ironwood Pharmaceuticals, Inc.* Isis Pharmaceuticals, Inc.* (a) Karyopharm Therapeutics, Inc.* Keryx Biopharmaceuticals, Inc.* (a) Kindred Biosciences, Inc.*

KYTHERA Biopharmaceuticals, Inc.*

Lexicon Pharmaceuticals, Inc.* Ligand Pharmaceuticals, Inc.* MacroGenics, Inc.* MannKind Corp.* (a)

Merrimack Pharmaceuticals, Inc.* (a)

MiMedx Group, Inc.* (a) Mirati Therapeutics, Inc.* Momenta Pharmaceuticals, Inc.* NanoViricides, Inc.*

Navidea Biopharmaceuticals, Inc.* (a)

NeoStem, Inc.* Neuralstem, Inc.* Neurocrine Biosciences, Inc.* NewLink Genetics Corp.* (a) Northwest Biotherapeutics, Inc.* Novavax, Inc.* NPS Pharmaceuticals, Inc.* Ohr Pharmaceutical, Inc.* OncoMed Pharmaceuticals, Inc.* Oncothyreon, Inc.* Ophthotech Corp.* (a) Opko Health, Inc.* (a) Orexigen Therapeutics, Inc.* (a) Organovo Holdings, Inc.* Osiris Therapeutics, Inc.* (a) OvaScience, Inc.* PDL BioPharma, Inc. (a)

Peregrine Pharmaceuticals, Inc.* (a)

Portola Pharmaceuticals, Inc.* Progenics Pharmaceuticals, Inc.* Prothena Corp. PLC* PTC Therapeutics, Inc.* Puma Biotechnology, Inc.* Raptor Pharmaceutical Corp.* (a) Receptos, Inc.* Regado Biosciences, Inc.* Regulus Therapeutics, Inc.* Repligen Corp.* Retrophin, Inc.* Rigel Pharmaceuticals, Inc.* Sangamo BioSciences, Inc.* Sarepta Therapeutics, Inc.* (a) Spectrum Pharmaceuticals, Inc.* Stemline Therapeutics, Inc.*

Sunesis Pharmaceuticals, Inc.* (a) Synageva BioPharma Corp.* Synergy Pharmaceuticals, Inc.* (a) Synta Pharmaceuticals Corp.* TESARO, Inc.* TG Therapeutics, Inc.* (a)

Threshold Pharmaceuticals, Inc.* (a)

Ultragenyx Pharmaceutical, Inc.* Vanda Pharmaceuticals, Inc.* (a) Verastem, Inc.* Versartis, Inc.* Vital Therapies, Inc.* Xencor, Inc.* XOMA Corp.* ZIOPHARM Oncology, Inc.* (a)

Health Care Equipment & Supplies 3.0% Abaxis, Inc. (a) ABIOMED, Inc.* (a) Accuray, Inc.* (a) Analogic Corp. AngioDynamics, Inc.* Anika Therapeutics, Inc.* Antares Pharma, Inc.* (a) AtriCure, Inc.* Atrion Corp. Cantel Medical Corp. Cardiovascular Systems, Inc.* Cerus Corp.* (a) CONMED Corp. CryoLife, Inc. Cyberonics, Inc.* Cynosure, Inc. “A”* Derma Sciences, Inc.* Dexcom, Inc.* Endologix, Inc.* Exactech, Inc.* Genmark Diagnostics, Inc.* Globus Medical, Inc. “A”* Greatbatch, Inc.* Haemonetics Corp.* HeartWare International, Inc.* ICU Medical, Inc.* Inogen, Inc.* Insulet Corp.* (a) Integra LifeSciences Holdings* Invacare Corp. K2M Group Holdings, Inc.* LDR Holding Corp.* Masimo Corp.* Meridian Bioscience, Inc. Merit Medical Systems, Inc.* Natus Medical, Inc.* Neogen Corp.* NuVasive, Inc.* NxStage Medical, Inc.* OraSure Technologies, Inc.* Orthofix International NV* Oxford Immunotec Global PLC* PhotoMedex, Inc.* (a) Quidel Corp.* (a) Rockwell Medical, Inc.* (a)

4,394

194,698

7,740

194,584

14,932

131,402

2,414

188,871

4,841

79,054

2,806

130,002

22,505

60,088

5,331

97,984

299

97,474

6,590

241,326

5,380

167,641

13,851

57,482

5,294

233,730

5,363

47,999

5,220

326,041

4,342

92,267

4,404

50,910

14,575

578,044

12,452

189,395

1,915

48,315

8,094

109,512

12,794

306,032

4,868

238,824

10,125

357,210

3,305

292,492

2,609

158,653

1,014

22,876

10,780

427,643

4,854

228,429

6,253

114,868

1,717

25,549

3,231

80,807

9,413

222,147

8,018

165,491

8,358

126,206

6,252

157,175

7,132

288,632

9,065

322,442

11,965

171,937

10,878

93,660

3,549

128,651

2,529

42,563

2,495

30,564

5,588

123,551

8,048

96,496

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Value ($)

9,629

62,781

4,172

437,226

18,247

74,265

11,295

46,197

3,751

116,694

4,570

42,912

10,187

40,341

1,294

58,088

6,497

105,121

4,083

36,992

1,349

37,826

1,007

27,431

2,959

34,384

16,323

74,923

15,684

63,207

17,320,499

The accompanying notes are an integral part of the financial statements.

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