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Figure 1 – Schematic of a nerve synapseii

Side Effects:

Arrhythmias

Myocardial depression

Laryngeal spasm

Cough

Sneezing

Hypersensitivity reactions

Rash

Injection-site reactions

Contraindications:

Breast-feeding, Porphyria, myotonic dystrophy

Contra-indicated if the anaesthetist is not confident of being able to maintain the airway (e.g. in the presence of a tumour in the pharynx or larynx). Extreme care is required in surgery of the mouth, pharynx, or larynx and in patients with acute circulatory failure (shock) or fixed cardiac output.

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