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  • TRIPLE ASSESSMENT TO EXCLUDE

MALIGNANCY.

  • REASSURE

  • EPO – has been withdrawn from Medicines Control Agency

    • 2 double blinded RCT – Blommers J et al. Am J Obstet Gyaecol. 2002 Khoo SK et al. Med J Aust. 1990

  • PHYTOESTROGENS (Soya Milk) some efficacy

  • SECOND LINE TREAMENT –

  • Tamoxifen 10mg daily – BUT NOT FDA APPROVED STILL AS AN INDICATION

    • DB RCT using tamoxifen 20mg vs placebo

– 72% PAIN FREE AT 1yr.RECURRENT PAIN ONLY IN 25%. ADVERSE EFFECTS IN 21%

GEMB group Argentine. Breast. 1997

  • Danazol 200mg daily. More side effects

  • Tam 10mg vs Danazol 200mg – Tamoxifen superior

Kontostolis. Gyn Endo 1997

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