Specific Systems of Treatment
by the Nazis, and imprisoned for 18 months in Italy. While there, he reasoned that there must be a substance which could induce rapid, uncon- trolled growth in animals; which, in turn, should set up the body defenses against the unregu- lated growth.
Meanwhile, Steven’s older brother, Marco who had also been captured, was able to arrange help through wealthy friends in Rome. Freed, they all fled to Argentina.
With the remnants of his fortune, Marco un- derwrote his brother’s initial experiments. Steven was certain there was a growth-regulating factor in the body. It was well-known that any animal tissue grown artificially multiplied indefinitely, as long as there was nourishment for the cells. It is true that they grow slowly, but there was no growth regulation governing them. These same tissues, inside the body, maintained an orderly growth pattern. What caused the miracle of growth regu- lation?
(Later researchers demonstrated a growth- regulating factor. Tissues of an adult frog were placed within a tadpole, and the tadpole immedi- ately stopped growing. The growth-stoppage fac- tor, in the adult tissues, were stronger than the growth-stimulant factors in the tadpole. Similar effects have been observed in cockroaches and caterpillars.)
But Durovic was searching, not for an anti- growth element, but an anti-abnormal growth sub- stance.
A related problem would be how to get the ani- mal to produce this growth-regulating factor. Ap- parently not by injecting with cancer tissue. That had been tried repeatedly by many earlier research- ers, in an attempt to produce antibodies against cancer. Such efforts generally met with failure.
During his early years in Buenos Aires, Durovic worked with cattle, injecting various substances into them. Then he would draw blood, hoping to find a defense substance which had been pro- duced.
came to mind that perhaps he had not been giving a powerful enough jolt to the body defenses, in order to produce the growth factor in recoverable amounts.
But what foreign bodies would produce the fastest growth? Bacteria? viruses? Perhaps it would be a fungus; he recalled his work back in Paris.
Then one day as he was half dozing, he re- called the rich fields of his ancestral farmlands, and cows and horses grazing there. Then the thought flashed into mind: Among his father’s horses and cows, sometimes there had appeared a strange disease. It began as a tiny growth, usu- ally on the side of the neck or jaw. Within a few weeks, the growth would burgeon into a huge tu- mor. The horse would become very sick and die, but some would recover and the tumor would to- tally disappear.
This thought was the moment of breakthrough. Surely, this was one of the fastest-growing liv- ing forms of animal tissue. When the horse re- covered, something in the horse halted the rapid growth by killing the invading cells. —And all this was done in a matter of weeks!
Checking into this, Durovic found that the growth was caused by a fungus, Actinomyces bovis, commonly known as “lumpy jaw.”
Immediately, he switched to horses and even- tually had injected hundreds of horses with ex- tracts of Actinomyces. Their blood had yielded about a half-teaspoon of a whitish powder he believed was the growth-control regulator for which he was searching.
The average yield from a horse was so small that it was almost invisible, yet it was so potent that it could protect the hundreds of pounds of a horse from a foreign growth within his body.
Strangely enough, some horses yielded noth- ing while others were relatively rich producers of the substance.
Trying out the substance on old dogs with natu- ral cancers, Durovic found the cancers shrank no- ticeably; some even disappeared.
Eventually, he came across a substance, stimu- lated by the reticuloendothelial system (a body de- fense mechanism) which, although ineffective against cancer, tended to lower high blood pres- sure.
Naming it Kositerin, he tried it on 150 patients at the Durand Hospital. Since his brother’s funds were nearly exhausted, they welcomed the help of a group of businessmen who wanted to sponsor the work, in order to reap profits from the forth- coming medicine.
While still testing the substance, his thoughts turned back to the cancer research. The thought
Independent tests, done by friends at the School of Veterinary Medicine, University of Buenos Aires, confirmed his work.
By this time he was ready to go to the United States, where he could have both his anti-cancer and his high blood pressure substances tested fur- ther.
Sealing 500 ampules, each containing a tiny fraction of the mysterious substance, he said good- bye to his brother, boarded a plane and flew to Chicago, known to be an important medical cen- ter.
Durovic had another reason for going to Chi-