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First, some general info…
Venous thrombosis/thrombophlebitis: both these terms are used to describe the inflammatory
response of a vessel wall that is caused by thrombus inside a superficial or deep vein
Thrombi in the legs are classified as either deep venous thrombi or superficial venous thrombi.
Composition of thrombus over time:
Early: venous thrombus composed of platelets and fibrin
Later: RBCs become interspersed in the fibrin and thrombus starts to propagate in the direction of
Vessel changes due to thrombosis:
Vessel structural changes can be minimal or can involve granulocyte infiltration, loss of endothelium, and/or edema.
Vessel flow may be diminished or obstructed by thrombi. Thrombi may dislodge, forming thromboemboli.
Now, onward to the disorders…
Venous Thrombosis – Deep Venous Thrombosis (DVT) Clinical Presentation:
May be asymptomatic.
Symptoms can include:
Calf or thigh discomfort, esp when standing or walking
Unilateral leg swelling
Complication of post phlebitic syndrome may present with:
Chronic leg swelling
Complication of pulmonary embolism (PE) may present with:
Pleuritic chest pain