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Common Congenital Heart Lesions - page 49 / 126

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49 / 126

49 of 126

  • Antiplatelets (ie. Aspirin, Thienopyridine, & GP IIb-IIIa antagonists)

  • Unfractionated Heparin—given for 1-2 days to prevent thromboembolism in patients with atrial fibrillation, LV thrombus, or large wall motion abnormality (b/c a thrombus can form there)

  • Beta-Blockers

  • Nitrates

For more detail on these agents, refer to “Acute Treatment of UA & NSTEMI”

Adjunctive Therapies for both STEMI & NSTEMI

  • Ace Inhibitors: limits adverse ventricular remodeling &reduces the

incidence of CHF, recurrent ischemia, & mortality following an MI

*The effects of ACE Inhibitors is additive to that of aspirin & Beta-Blockers & is extremely useful in high risk patients w/ LV systolic dysfunction

  • Statins: cholesterol lowering; may also improve endothelial

dysfunction, inhibit platelet aggregation, & impair thrombus formation

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