X hits on this document

50 views

0 shares

0 downloads

0 comments

12 / 27

3M™ EZ Sand Flexible Parts Repair PN 05887, 05891, 05893, 05895, 05896 - Part B (Base)

02/06/14

Reproductive Toxicity

Reproductive and/or Developmental Effects

Name

Route

Bisphenol A-Epichlorohydrin Polymer

Ingestion

Bisphenol A-Epichlorohydrin Polymer

Ingestion

Bisphenol A-Epichlorohydrin Polymer

Dermal

Value

Species

Not toxic to female reproduction

Rat

Not toxic to male reproduction

Rat

Not toxic to development

Rabbit

Ingestion

Not toxic to development

Ingestion

Not toxic to development

Ingestion

Not toxic to development

Ingestion

Not toxic to female reproduction

Ingestion

Not toxic to male reproduction

Ingestion

Not toxic to development

Inhalation

Not toxic to female reproduction

Inhalation

Not toxic to development

Ingestion

Some positive developmental data exist, but the data are not sufficient for classification Toxic to male reproduction

Ingestion

Inhalation

Toxic to male reproduction

Bisphenol A-Epichlorohydrin Polymer

Talc

Limestone

Filler

Filler

Filler

Epichlorohydrin

Epichlorohydrin

Epichlorohydrin

Epichlorohydrin

Epichlorohydrin

Rat

Rat

Rat

Rat

Rat

Rat

Rat

Multiple animal species Multiple animal species Rat

Rat

Test Result

NOAEL 750 mg/kg/day NOAEL 750 mg/kg/day NOAEL 300 mg/kg/day

NOAEL 750 mg/kg/day NOAEL 1,600 mg/kg

NOAEL 625 mg/kg/day

NOAEL 509 mg/kg/day NOAEL 497 mg/kg/day NOAEL 1,350 mg/kg/day NOAEL 0.2 mg/l NOAEL 0.09 mg/l

NOAEL 160 mg/kg/day

LOAEL 6.25 mg/kg/day NOAEL 0.02 mg/l

Exposure Duration 2 generation

2 generation

during organogenesi s 2 generation

during organogenesi s premating & during gestation 1 generation

1 generation

during organogenesi s 10 weeks

during organogenesi s during gestation

23 days

10 weeks

Route

Target Organ(s)

Value

Species

Inhalation

respiratory system

All data are negative

Rat

Inhalation

respiratory irritation

Some positive data exist, but the data are not sufficient for classification May cause respiratory irritation

Inhalation

respiratory irritation

Human

Inhalation

liver

Some positive data exist, but the data are not sufficient for classification

Human

Test Result

Exposure Duration 90 minutes

NOAEL 0.812 mg/l NOAEL Not available

NOAEL not available NOAEL not available

occupational exposure occupational exposure

Target Organ(s)

Specific Target Organ Toxicity - single exposure

Name

Limestone

Stearic Acid

Epichlorohydrin

Epichlorohydrin

Name

Route

Target Organ(s)

Bisphenol A-

Dermal

liver

Epichlorohydrin Polymer

Bisphenol A- Epichlorohydrin Polymer

Dermal

nervous system

Value

Species

Some positive data exist, but the data are not sufficient for classification All data are negative

Rat

Rat

Specific Target Organ Toxicity - repeated exposure

Test Result

NOAEL 1,000 mg/kg/day NOAEL 1,000

Exposure Duration 2 years

13 weeks

Page

10

of

13

Document info
Document views50
Page views50
Page last viewedFri Oct 28 16:44:09 UTC 2016
Pages27
Paragraphs1114
Words8667

Comments