Two views of the collagen cross- linking machine
and safety evaluations show no apoptosis of endothelial cells, if the corneal thick- ness is at least 400 microns pre-treat- ment and there has been no change in the clarity of the cornea or the lens. Professor Seiler has, however, reported that the long-term data available in rabbits treated with the riboflavin/UV light cross-linking technique, show that keratoconus eventually begins to progress again. 7
The future for collagen cross-linking is a very exciting one. It may also be used to treat other ectatic disorders – pellu- cid marginal degeneration, post-Lasik keratectasia – and because of its low cost, it may have applications in developing
countries, where corneal grafts are not readily available. ●
References 1 Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res, 1998;66:97-103. 2 Wollensak, G, Spoerl E, Wilsch M, Seiler T. Endothelial cell damage after riboflavin- ultraviolet-A-treatment in the rabbit. J Cataract Refract Surg, 2003;29:1786-1790. 3 Wollensak G, Wilsch M, Spoerl E, Seiler T. Collagen fiber diameter in the rabbit cornea after collagen-crosslinking. Cornea, 2004;23:503-507 4 Spoerl E, Wollensak G, Dittert DD, Seiler T. Thermomechanical behaviour
of collagen cross-linked porcine cornea. Ophthalmologica, 2004;218:136-140. 5 Spoerl E, Seiler T. Techniques for stiffening the cornea. J Refract Surg, 1999;15:711- 713 6 Hagele G, Boxer Wachler BS. Corneal collagen crosslinking with riboflavin (C3-R) for corneal stabilization. Presented at the international congress of corneal cross linking (CCL). December 9-10, 2005. Zurich, Switzerland. 7 Wollensak G, Spoerl E, Reber F, Seiler T. Keratocyte cytotoxicity of riboflavin/UVA treatment in vitro. Eye, 2004;18:718-722.
Clare McDonnell is an optometrist
working in the refractive surgery sector
Image your patient in just 3 clicks...
...with Kowa Non myd imaging systems from Keeler
mASSIve 10 megapixel
One screen - no complicated pop up windows, no getting 'lost' in a labyrinth of software complexity
Two icon bars - simple yet powerful, one for routine imaging, the other for image processing
Three clicks - just three clicks on the mouse to image your patient, what can be simpler and faster
SpecIAl lImIted oFFer prIce
As easy as
The result - perfect pics.
Offer closes July 25th 2007. Not to be used in conjunction with any other offer. E&OE.
The unbeatable Kowa Non Myd 7 with Kowa's own VK-2 software features: 20° optical zoom for perfect disc examination, stereo disc imaging, one touch camera controls, one click red free image, motorised precision joystick, NHS compliant
Freephone 0800 521251 for further details
Keeler Ltd Clewer Hill Road Windsor Berkshire SL4 4AA Tel: +44 (0) 1753 857177 Fax: +44 (0)1753 827145 firstname.lastname@example.org www.keeler.co.uk
25.05.07 | Optician | 27