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Pediatric Residents International Track Seminar - page 16 / 34

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2/14/2015

Hossam M.Al-Tatari, M.D.

16

Management, tetanus

Tetanus Immune Globulin (human) (TIG) :3000 to 6000 U IM for children and adults.

In tetanus neonatorum: smaller doses (as small as 500 U)

Some recommend infiltration around the wound. The efficacy has not been proven.

Where TIG is not available, equine tetanus antitoxin may be available. It is administered as a single dose of 50 000 to 100 000 U after testing for sensitivity.Part of this dose (20 000 U) should be given intravenously.

Intravenous Immune Globulin contains antibodies to tetanus and can be considered for treatment if TIG is not available.

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