X hits on this document

123 views

0 shares

0 downloads

0 comments

12 / 52

P6: Fungal Autoinducers, U. Ugalde

Title:

Dr

First Name:

Unai

Family Name:

Ugalde

Position:

Senior Lecturer

Name of organization:

Universidad del País Vasco/ Euskal Herriko Unibersitatea

Address:

Bioquímica II, Facultad de Qímica, Aptdo. 1072

Postcode:

20080

City:

San Sebastian

Country:

Spain

Telephone:

+34943018180

Fax:

+34943212236

E-mail:

qppugmau@sc.ehu.es

Website:

Proposed Title

Fungal Autoinducers

Abstract

It has been recently discovered that filamentous fungi produce small molecular weight autoinducers to report on the extracellular environment. Conidiogenone has been reported to act as the molecule which reports on the emergence to the air in Penicillium cyclopium (1). This autoinducer is capable of arresting growth and promoting spore production in liquid media when externally added at nanoMolar concentrations. Along with conidiogenone, other autoinducers are now being searched for which have antagonistic effects, and emerging evidence supports the view that a collection of these newly discovered agents act in the control of colony morphology in filamentous fungi. Since these agents act on the producing organism, the risk of resistence with repeated use is minimised. In addition, the range of concentration at hwich they act is below the detection levels of the immune system, and they are natural compounds which are biodegradable. In contrast to these appealing features, autoinducers cannot be used to kill a target organism. Considering these features in a perspective, autoinducers may find interesting applications in food industry, sustainable agriculture, and possibly as a complement to other agents in the clinical field. The targets of autoinducers are unknown, but could offer good opportunities for the development of new antifungal agents.

A. Enterprises Corner

Enterprises looking for complementary partners in research arena and

x

Researchers offer their findings for technology transfer to enterprises

B. Research Corner

x

Research institutions looking for partners for joint research venture

Potentially interested for continuation of projects preparations on Tuesday afternoon 1 st July

Keywords:

Autoinducers

Received: 15/6/2003

Document info
Document views123
Page views123
Page last viewedWed Dec 07 22:41:09 UTC 2016
Pages52
Paragraphs1880
Words16621

Comments