X hits on this document

136 views

0 shares

0 downloads

0 comments

21 / 30

Structure Summary

Tykerb Inactive-like conformation

Tarceva Active-like conformation

C helix

Activation Loop

C terminal tail

closed down ATP cleft activation loop - inactive conformation incorrect arrangement of catalytic residues C-terminal tail not accessible

open ATP cleft activation loop - active conformation correct arrangement of catalytic residues C-terminal tail extended

Document info
Document views136
Page views136
Page last viewedTue Jan 24 03:23:29 UTC 2017
Pages30
Paragraphs319
Words1235

Comments