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Lapatinib + Paclitaxel: PR

63 yo female with metastatic IBC (ErbB1+/ErbB2 3+). 5 prior metastatic regimens; prior docetaxel, trastuzumab.

Treatment duration 9 months: 6 cycles 175 mg/m2 paclitaxel (q3 wk) + 1500 mg/day lapatinib; continued treatment with lapatinib alone.

Pretreatment

After Cycle 6

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