THEME 1: Health
Problems to be solved and results:
Estimation of FRO intensity in rats liver, heart, brain and blood serum at an experimental toxic hepatitis, myocardium infarction, brain ischemia and hyperthyroidism and also at introduction of substances-protectors.
Definition of AOS components activity at pathological conditions and at introduction of protectors (melatonin, thioctic acid, citrate, several synthetic substances).
Definition of activity of some central metabolic pathways enzymes (CS, АH, NAD- and NADP-IDH, SDH, NAD- and NADP-MDH, G6PDH, 6PGDH) in conditions of a pathology and at action of substances-protectors, and research of these enzymes properties with purified enzyme preparations use.
Study of peculiarities of oxidative metabolism enzymes expression and clarification of their induction and repression possibility at oxidative stress development and protectors action.
Partners already acquired: Miguel A.A. Pinheiro de Carvalho, University of Madeira, Funshal, Portugal
1.2. Translating research for human health
5. Prof. Eduard Minakov
Organization Name: N.N. Burdenko Voronezh state medical academy
Position in Organization:Head of Hospital Surgery Department
Telephone: +7 –4732 – 13-46-01
Address: 10, Studencheskya street, 394000, Voronezh, Russian Federation
Proposal/Expertise: Modern technologies of diagnostics, treatment, prevention of diseases