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Russian regional scientists project proposals for participation in FP7 - page 5 / 62

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THEME 1: Health

Problems to be solved and results:

Estimation of FRO intensity in rats liver, heart, brain and blood serum at an experimental toxic hepatitis, myocardium infarction, brain ischemia and hyperthyroidism and also at introduction of substances-protectors.

Definition of AOS components activity at pathological conditions and at introduction of protectors (melatonin, thioctic acid, citrate, several synthetic substances).

Definition of activity of some central metabolic pathways enzymes (CS, АH, NAD- and NADP-IDH, SDH, NAD- and NADP-MDH, G6PDH, 6PGDH) in conditions of a pathology and at action of substances-protectors, and research of these enzymes properties with purified enzyme preparations use.

Study of peculiarities of oxidative metabolism enzymes expression and clarification of their induction and repression possibility at oxidative stress development and protectors action.

Partners already acquired: Miguel A.A. Pinheiro de Carvalho, University of Madeira, Funshal, Portugal

1.2. Translating research for human health

5. Prof. Eduard Minakov

Organization Name: N.N. Burdenko Voronezh state medical academy

Position in Organization:Head of Hospital Surgery Department

E-mail address:kgh@email.ru

Telephone: +7 –4732 – 13-46-01

Address: 10, Studencheskya street, 394000, Voronezh, Russian Federation

Proposal/Expertise: Modern technologies of diagnostics, treatment, prevention of diseases

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