Triad: urethritis, conjunctivitis, and arthritis
Can’t see, can’t pee, can’t climb a tree!
May also be other features that involve the skin , mucous membranes, GI tract, and cardiovascular system
American Rheumatism Association - criterion of peripheral arthritis of more than 1 month duration, in association with urethritis and/or cervicitis
Young men of HLA-B27 genotype