X hits on this document

491 views

0 shares

0 downloads

0 comments

131 / 170

12

why we have such need. I think Ms. Close did a great job of describing why it’s

13

important for us to consider, why it’s important to take care of diabetes early on. I am

14

still trying to figure out the relationship between actual macrovascular events and

15

diabetes control. I think there are a number of studies and we have been looking at that.

16

That’s still an issue. Just because diabetes is a risk factor for a later development of

17

these, it doesn’t mean that the administration of a drug in the context of coronary artery

18

diseases is safe.

4

higher events. I would love to - you should compare the event rate, which I don’t

5

remember off the top of my head, but I would be happy to compare the event rate from

6

CARDS to the event rate we are seeing here, which is 5 myocardial infractions out of a

7

4,000-patient trial where supposedly they are at high risk for myocardial infractions,

8

which is not the case. What was the first?

20

have a placebo group in these trials. You can look at the placebo event rate. The placebo

21

event rate is lower than most hypertension studies. I mean so, you know, it - yes, these

22

patients will have a lot of events if we follow them for 10 years. These are not the kind

23

of patients that will have a lot of events in six months or a year and all we have to do is

19

If you want to call this a high-risk population that’s fine; we, fortunately,

Scribes, LLC Toll Free 1-800-675-8846 www.scribesllc.com

1

cardiovascular disease, so they haven’t declared themselves clinically, but the trial

2

itself certainly showed that they were at high risk for events.

9

DR. PARKS: Your comments or your thoughts on diabetes already being

3

130

DR. TEERLINK: That trial purposely tried to enroll patients who were at

10

11

observed or established as a cardiovascular or CHD risk equivalent.

DR. TEERLINK: It absolutely is. I think that’s why we are here. That’s

Document info
Document views491
Page views491
Page last viewedThu Dec 08 12:05:50 UTC 2016
Pages170
Paragraphs7975
Words54271

Comments