DR. WOLF: Yes.
DR. TEERLINK: Right, and what I am asking for is since that's
better by more granularity in terms of the degree of renal failure and renal discomfort and
renal insufficiency at baseline as well as a breakdown of the details of the micro-vascular
complications at baseline.
Scribes, LLC Toll Free 1-800-675-8846 www.scribesllc.com
extraordinarily mild, I don't think necessarily representative of the diabetes population as
a whole that will eventually be treated. I’m asking for what experience do we have in
patients who have, what's the breakdown of those patients who have a creatinine
clearance less than 80 in little finer delineations?
helpful. Finally, I am trying to figure out how - one of the major concerns of other agents
you say that safety and tolerability of agents is a major concern and you mentioned that
DR. WOLF: So, approximately 15% to 16% of our population had mildly
impaired renal function based on a Cockcroft Gault Equation?
vascular complications that are present in this population. So if you could provide that
data later that would be helpful. The final issue is – or if you have it now, I'm happy to
DR. TEERLINK: Are you talking about, that’s the 80 - less than 80
DR. TEERLINK: All right, if you could provide that data, that would be
say that now, I am sorry.
DR. WOLF: Are you asking for a description of the baseline
characteristics of the population?
DR. TEERLINK: Yeah, breakdown of the renal - kind of breakdown
DR. WOLF: So, most of those patients came into the range of a creatinine
clearance between 50 to 80 and which would be in the mild range.