X hits on this document

528 views

0 shares

0 downloads

0 comments

67 / 170

14

DR. WOLF: Yes.

15

DR. TEERLINK: Right, and what I am asking for is since that's

7

better by more granularity in terms of the degree of renal failure and renal discomfort and

8

renal insufficiency at baseline as well as a breakdown of the details of the micro-vascular

9

complications at baseline.

Scribes, LLC Toll Free 1-800-675-8846 www.scribesllc.com

66

16

extraordinarily mild, I don't think necessarily representative of the diabetes population as

17

a whole that will eventually be treated. I’m asking for what experience do we have in

18

patients who have, what's the breakdown of those patients who have a creatinine

19

clearance less than 80 in little finer delineations?

23

helpful. Finally, I am trying to figure out how - one of the major concerns of other agents

24

you say that safety and tolerability of agents is a major concern and you mentioned that

10

11

DR. WOLF: So, approximately 15% to 16% of our population had mildly

impaired renal function based on a Cockcroft Gault Equation?

12

13

1

vascular complications that are present in this population. So if you could provide that

2

data later that would be helpful. The final issue is – or if you have it now, I'm happy to

millimeters?

DR. TEERLINK: Are you talking about, that’s the 80 - less than 80

22

DR. TEERLINK: All right, if you could provide that data, that would be

3

4

say that now, I am sorry.

DR. WOLF: Are you asking for a description of the baseline

5

6

characteristics of the population?

DR. TEERLINK: Yeah, breakdown of the renal - kind of breakdown

20

21

DR. WOLF: So, most of those patients came into the range of a creatinine

clearance between 50 to 80 and which would be in the mild range.

Document info
Document views528
Page views528
Page last viewedSat Dec 10 03:17:26 UTC 2016
Pages170
Paragraphs7975
Words54271

Comments