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    3) On skeletal and bone

   a)    Estrogen has dual effect on skeletal growth.

          Estrogen increases the osteoblastic activity at the time of   

          puberty.    

    b)   Estrogen  are responsible for the oval shape of the female  

           pelvic

    c)  Estrogen promotes the deposition of bone matrix  (Estrogen      

         protects against bone loss in women)

     4) On the breast

   a)  Estrogen enhance the development and growth of the    

        tubular duct system and nipples of mammary gland.

   b)  Estrogen causes fat deposition in the breast which cause    

        breast enlargement at puberty.

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