“SAGE agreed that the BCG position paper should be
updated to reflect this change and provide guidance
to national policy-making bodies, recognizing the
complexity of the decision-making process and the lack of information as well as the necessary infrastructure to perform adequate risk assessment in individual children.
Among HIV-infected children, the benefits of potentially preventing severe TB are outweighed by the risks associated with the use of BCG vaccine. GACVS therefore advised WHO to change its recommendation such that children who are known to be HIV-infected, even if asymptomatic, should no longer be immunized with BCG vaccine.”