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Ultrafiltration

RAPID-CHF Trial

40 patients

ADHF and Renal Insufficiency (Cr >1.5)

Ultrafiltration had significant increase in fluid removal after 24 hours

4650 L vs 2838L

UNLOAD Trial

200 patients

Renal insufficiency was not a criteria for inclusion

Standard care vs ultra filtration

48 Hours 4.6 L vs 3.3L

90 Days fewer rehospitalizations .22 vs .46 and fewer unscheduled clinic visits 21 vs 44

Option in the setting of failed diuretic and vasodilator therapy

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