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Dopamine and Dobutamine

Dopamine:

Vasodilator of Renal, Coronary, splanchnic and Cerebral Vascular beds

Hypotensive patients

Drawbacks: arrhythmia, increased pulmonary vascular resistance and increased afterload

Dobutamine, Class IIa, C

Hypotension and low Urine output

Beta 1 and 2 agonist

At high doses increases SVR

Additive effect with Phosphodiesterase inhibitors

Draw Backs- arrhythmia, reflex decrease in sympathetic tone

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