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Cold-Activated Brown Adipose Tissue in Healthy Men

etal muscle to thermogenesis induced by ephedrine in man. Am J Physiol 1985;248: E507-E515. 10. Himms-Hagen J. Does brown adipose tissue (BAT) have a role in the physiology or treatment of human obesity? Rev Endocr Metab Disord 2001;2:395-401. 11. Hany TF, Gharehpapagh E, Kamel EM, Buck A, Himms-Hagen J, von Schulthess GK. Brown adipose tissue: a factor to con- sider in symmetrical tracer uptake in the neck and upper chest region. Eur J Nucl Med Mol Imaging 2002;29:1393-8. 12. Cohade C, Osman M, Pannu HK, Wahl RL. Uptake in supraclavicular area fat (“USA-Fat”): description on 18F-FDG PET/CT. J Nucl Med 2003;44:170-6. 13. Yeung HW, Grewal RK, Gonen M, Schoder H, Larson SM. Patterns of (18)F- FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET. J Nucl Med 2003;44:1789-96.

  • 14.

    Nedergaard J, Bengtsson T, Cannon

    • B.

      Unexpected evidence for active brown

adipose tissue in adult humans. Am J Physiol Endocrinol Metab 2007;293:E444- E452. 15. Rousseau C, Bourbouloux E, Campion L, et al. Brown fat in breast cancer patients: analysis of serial (18)F-FDG PET/CT scans. Eur J Nucl Med Mol Imaging 2006;33:785- 91.

16. Chiba S, Katsuragi I, Simada T, et al. Evaluation of human brown adipose tis- sue using positron emission tomography, computerised tomography and histochem- ical studies in association with body mass index, visceral fat accumulation and insu- lin resistance. Obes Rev 2006;7:Suppl 2:

  • 87.

    abstract.

  • 17.

    Sturkenboom MGG, Franssen EJF,

Berkhof J, Hoekstra OS. Physiological up- take of [18F]fluorodeoxyglucose in the neck and upper chest region: are there predictive characteristics? Nucl Med Com- mun 2004;25:1109-11. 18. Ravussin E, Lillioja S, Anderson TE, Christin L, Bogardus C. Determinants of 24-hour energy expenditure in man: methods and results using a respiratory chamber. J Clin Invest 1986;78:1568-78. 19. van Marken Lichtenbelt WD, Daanen HAM, Wouters L, et al. Evaluation of wire- less determination of skin temperature using iButtons. Physiol Behav 2006;88: 489-97. 20. ISO 9886. Evaluation of thermal strain by physiological measurements. Geneva: International Standards Organization, 2004. 21. Rubinstein EH, Sessler DI. Skin-sur- face temperature gradients correlate with fingertip blood flow in humans. Anesthe- siology 1990;73:541-5.

22. van Ooijen AMJ, van Marken Lichten- belt WD, van Steenhoven AA, Westerterp K. Seasonal changes in metabolic and temperature responses to cold air in hu- mans. Physiol Behav 2004;82:545-53. 23. Cohade C, Mourtzikos KA, Wahl RL. “USA-Fat”: prevalence is related to ambi- ent outdoor temperature-evaluation with 18F-FDG PET/CT. J Nucl Med 2003;44: 1267-70. 24. Wijers SLJ, Schrauwen P, Saris WHM, van Marken Lichtenbelt WD. Human skel- etal muscle mitochondrial uncoupling is associated with cold induced adaptive ther- mogenesis. PLoS ONE 2008;3(3):e1777. 25. Kajimura S, Seale P, Tomaru T, et al. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev 2008; 22:1397-409. 26. Seale P, Kajimura S, Yang W, et al. Transcriptional control of brown fat de- termination by PRDM16. Cell Metab 2007; 6:38-54. 27. Seale P, Bjork B, Yang W, et al. PRDM16 controls a brown fat/skeletal muscle switch. Nature 2008;454:961-7. 28. Cannon B, Nedergaard J. Develop- mental biology: neither fat nor flesh. Na- ture 2008;454:947-8. Copyright © 2009 Massachusetts Medical Society.

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