PREMENSTRUAL SYNDROME AND PAINFUL MENSTRUATION Sampallis et al reported in 2003 on a study of efficacy of krill oil in managing the premenstrual syndrome (PMS) and dysmenorrhea (painful and difficult menstruation). In this double blind, randomized trial, patients with diagnosed PMS were treated for three months with either krill oil or ordinary fish oil. Validated questionnaires were used to assess the changes in symptoms. The resultant data showed a significant improvement on interim and final evaluations for the krill oil group as compared to baseline evaluation, and as well as when the krill oil group was compared with the fish
Editor’s comments: All of these studies utilized a product trademarked “NKO” and manufactured by Neptune Biotechnologies and Bioressources, Inc. of
Laval, Quebec, unique patented
Canada. This company process of recovering the
has a krill oil
unique formulation of these polyunsaturated fatty acids. The contains Vitamins A and E, and a astaxanthin, an antioxidant. The
two long-chain preparation also substance called company claims
vitamins A and E. The research Quebec or Ontario, Canada.
was all Lead
oil group. analgesics
Also, significantly were consumed by
lower amounts of the krill oil group
when interim and final evaluations with baseline, and also when krill
were compared oil users were
taking fish oil.
dysmenorrhea and was more
and the emotional symptoms of PMS effective than ordinary fish oil for the
management of PMS. Deutsch, L. Evaluation of the Effect of Neptune Krill Oil on Chronic Inflammation and Arthritic Symptoms. Journal of the American College of Nutrition, 2007, Vol. 26, No. 1, pp. 39-48. Bunea, R. et al. Evaluation of the Effects of Neptune Krill Oil on the Clinical Course of Hyperlipidemia. Alternative Medicine Review, 2004, Vol. 9, No. 4, pp. 420-28. Sampalis, F. et al. Evaluation of the Effects of Neptune Krill Oil on the Management of Premenstrual Syndrome and Dysmenorrhea. Alternative Medicine Review, 2003, Vol. 8, No. 2, pp. 171-9.
paper has a
Bioressources. available from
Neptune krill oil (NKO brand) is health food stores or Internet
vendors. It appears to be the only brand used in clinical trials. The company recently entered into a research and development agreement with Nestlé to further investigate the health benefits of krill oil. In addition the company has an agreement with Yoplait to cooperate in the development of dairy products containing krill oil.
In addition to the three papers discussed above, there appear to be only two other studies of this oil
in journals covered Medicine (PubMed). published in 1994.
by the National Library of Both were rodent studies There is obviously a great
opportunity here interesting fish oil, NKO.
more research into this in particular the preparation
OMEGA-3 FATTY ACIDS AND ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD)
Attention-deficit hyperactivity disorder (ADHD) is a rapidly growing problem in the Western world. It is estimated that 5-10% of school-age children (mostly boys) suffer from the disorder. Major symptoms are difficulty in sustaining attention, hyperactivity, and impulsivity. ADHD is also associated with learning difficulties in reading, spelling, and math and may involve psychiatric problems that follow the child into adulthood. There is considerable evidence that ADHD is linked to a fatty acid deficiency or imbalance. Long-chain fatty acids such as EPA and DHA are essential to proper brain functioning and several studies involving children with ADHD have
shown that they are deficient in these essential fatty acids. Two recent studies relate to this topic.
IMPACT OF OMEGA-3 SUPPLEMENTATION ON AN INFLAMMATION MARKER IN ADHD PATIENTS Germano et al recently reported a study that involved testing omega-3 supplementation on both the fatty acid composition of plasma phospholipids and red blood cell phospholipids and as well observing any changes in two measures of the
extent of the ADHD. recruited a cohort aged
The 3.5 to
16 years and
controls and intervention
individuals diagnosed with ADHD. involved approximately 2.5 g/d of
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