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KRILL

OIL

FOR

MANAGEMENT

OF

PREMENSTRUAL SYNDROME AND PAINFUL MENSTRUATION Sampallis et al reported in 2003 on a study of efficacy of krill oil in managing the premenstrual syndrome (PMS) and dysmenorrhea (painful and difficult menstruation). In this double blind, randomized trial, patients with diagnosed PMS were treated for three months with either krill oil or ordinary fish oil. Validated questionnaires were used to assess the changes in symptoms. The resultant data showed a significant improvement on interim and final evaluations for the krill oil group as compared to baseline evaluation, and as well as when the krill oil group was compared with the fish

Editor’s comments: All of these studies utilized a product trademarked “NKO” and manufactured by Neptune Biotechnologies and Bioressources, Inc. of

Laval, Quebec, unique patented

Canada. This company process of recovering the

has a krill oil

which

yields

phospholipid

bound

poly

unsaturated

fatty

acids

EPA

and

DHA,

making

NKO

krill

oil

a

unique formulation of these polyunsaturated fatty acids. The contains Vitamins A and E, and a astaxanthin, an antioxidant. The

two long-chain preparation also substance called company claims

their

preparation

has

300

times

the

antioxidant

power done

of in

vitamins A and E. The research Quebec or Ontario, Canada.

was all Lead

researchers

were

either

from

McGill

University

or

oil group. analgesics

Also, significantly were consumed by

lower amounts of the krill oil group

when interim and final evaluations with baseline, and also when krill

were compared oil users were

compared

to those

conclude

that krill

taking fish oil.

The

oil

can

significantly

authors reduce

dysmenorrhea and was more

and the emotional symptoms of PMS effective than ordinary fish oil for the

management of PMS. Deutsch, L. Evaluation of the Effect of Neptune Krill Oil on Chronic Inflammation and Arthritic Symptoms. Journal of the American College of Nutrition, 2007, Vol. 26, No. 1, pp. 39-48. Bunea, R. et al. Evaluation of the Effects of Neptune Krill Oil on the Clinical Course of Hyperlipidemia. Alternative Medicine Review, 2004, Vol. 9, No. 4, pp. 420-28. Sampalis, F. et al. Evaluation of the Effects of Neptune Krill Oil on the Management of Premenstrual Syndrome and Dysmenorrhea. Alternative Medicine Review, 2003, Vol. 8, No. 2, pp. 171-9.

earliest

paper has a

coauthor

directly

working for

Neptune

the

University

Health

Network

Toronto.

Only

the

someone who

was

Technologies

and

Bioressources. available from

Neptune krill oil (NKO brand) is health food stores or Internet

vendors. It appears to be the only brand used in clinical trials. The company recently entered into a research and development agreement with Nestlé to further investigate the health benefits of krill oil. In addition the company has an agreement with Yoplait to cooperate in the development of dairy products containing krill oil.

In addition to the three papers discussed above, there appear to be only two other studies of this oil

in journals covered Medicine (PubMed). published in 1994.

by the National Library of Both were rodent studies There is obviously a great

opportunity here interesting fish oil, NKO.

for and

more research into this in particular the preparation

OMEGA-3 FATTY ACIDS AND ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD)

Attention-deficit hyperactivity disorder (ADHD) is a rapidly growing problem in the Western world. It is estimated that 5-10% of school-age children (mostly boys) suffer from the disorder. Major symptoms are difficulty in sustaining attention, hyperactivity, and impulsivity. ADHD is also associated with learning difficulties in reading, spelling, and math and may involve psychiatric problems that follow the child into adulthood. There is considerable evidence that ADHD is linked to a fatty acid deficiency or imbalance. Long-chain fatty acids such as EPA and DHA are essential to proper brain functioning and several studies involving children with ADHD have

shown that they are deficient in these essential fatty acids. Two recent studies relate to this topic.

IMPACT OF OMEGA-3 SUPPLEMENTATION ON AN INFLAMMATION MARKER IN ADHD PATIENTS Germano et al recently reported a study that involved testing omega-3 supplementation on both the fatty acid composition of plasma phospholipids and red blood cell phospholipids and as well observing any changes in two measures of the

extent of the ADHD. recruited a cohort aged

The 3.5 to

study, done

in Italy,

16 years and

included

controls and intervention

individuals diagnosed with ADHD. involved approximately 2.5 g/d of

The fish

International Health News

November 2007

Page 3

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