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VI- Coumarin containing drugs 1-Ammi visnaga Fruit (Fructus Ammi Visnagae)

Origin: the dried ripe fruit of Ammi visnaga F. Umbelliferae

Active constituents:

furanochromone bitter principle: khellin and visnagin.

Pyranocoumarin bitter principle: visnadin (a potent vasodialator).

Uses:

relax smooth muscle of the ureter, so used to ease the passage of renal caculi.

Khellin is antispasmodic given in renal and biliary colic, in bronchial asthma and in angina pectoris attacks.

Chemical tests:

Boil the powder with water for 1 min., add 1-2 drops of thid decoction to 1 cc solution of NaOH (1 in 1), shake, rose red colour is produced within 2 min.

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