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Goldzon Marina Alexandrovna - intern of chair of hospital therapy of Omsk state medical academy, tel.: 8(904)329-46-50; e-mail: magi-net@rambler.ru

Material Received 09.02.2010 г.

1322 Белова+

UDC 616.72-002:616-092.9

© S.V. Belova, 2010

Belova S.V. Simulation of experimental arthritis // Preventive and clinical medicine. – 2010. - № 2 (35). – Р.

Federal government agency «Saratov Research Institute of Traumatology and Orthopedics», Russia, 410002, Saratov, Chernyshevsky str., 148. Tel.: 8(845)223-04-13. e-mail: sarniito@yandex.ru

Summary: The possibility to model an experimental rheumatoid arthritis by means of a new method (Patent RU 2351021) is demonstrated. A good comparativeness of histological manifestations, hematological, cytological, biochemical and histomorphologic alterations by experimental animals and patients with rheumatoid arthritis as well as reliability and rapidity of an adequate reproduction of this pathology permits to recommend this new model for studying of pathogenesis, improving of diagnostic,s methods and approving of various schemes (with and without medicaments) of therapy of rheumatoid arthritis.

Key words: rheumatoid arthritis; pathogenesis; diagnostics and treatment.

References

1. Гриневич Ю.А. Определение иммунных комплексов в крови онкологических больных / Ю.А. Гриневич, А.И. Алферов // Лаб. дело. - 1984. - № 8. – С. 493-496.

2. Карякина Е.В. Клиническое значение определения гликозаминогликанов сыворотки крови и синовиальной жидкости при ревматоидном артрите / Е.В. Карякина // Вопр. ревматологии. - 1982. - № 4. – С. 31-34.

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