For Information OnlyBreast
MXPresence of distant metastasis cannot be assessed
M0No distant metastasis
Stage I T1# N0 M0
Stage IIA T0 N1 M0
T1# N1 M0
T2 N0 M0
Stage IIB T2 N1 M0
Stage IIIA T0 N2 M0
T1# N2 M0
T2 N2 M0
Stage IIIBT4 N0,N1,N2 M0
Stage IIICAny T N3 M0
Stage IVAny T Any N M1
# T1 includes T1mic.
For identification of special cases of TNM or pTNM classifications, the “m” suffix and “y,” “r,” and “a” prefixes are used. Although they do not affect the stage grouping, they indicate cases needing separate analysis.
indicates the presence of multiple primary tumors in a single site and is recorded in parentheses: pT(m)NM.
indicates those cases in which classification is performed during or following initial multimodality therapy (ie, neoadjuvant chemotherapy, radiation therapy, or both chemotherapy and radiation therapy). The cTNM or pTNM category is identified by a “y” prefix. The ycTNM or ypTNM categorizes the extent of tumor actually present at the time of that examination. The “y” categorization is not an estimate of tumor prior to multimodality therapy (ie, before initiation of neoadjuvant therapy).
indicates a recurrent tumor when staged after a documented disease-free interval, and is identified by the “r” prefix: rTNM.
designates the stage determined at autopsy: aTNM.
Tumor remaining in a patient after therapy with curative intent (eg, surgical resection for cure) is categorized by a system known as R classification, shown below.
RXPresence of residual tumor cannot be assessed
R0No residual tumor