Rutter teacher and parent questionnaires. J Child Psychol Psy- chiatry 1989;30:671–689.
Stevenson J. Evidence for a genetic etiology in hyperactivity in children. Behav Genet 1992;22:337–344.
Gilger JW, Pennington BF, DeFries C. A twin study of the etiology of comorbidity: attention deficit hyperactivity disorder and dyslexia. J Am Acad Child Adolesc Psychiatry 1992;31: 343–348.
Sherman D, Iacono W, McGue M. Attention deficit hyperactiv- ity disorder dimensions: a twin study of inattention and impul- sivity hyperactivity. J Am Acad Child Adolesc Psychiatry 1997; 36:745–753.
Hudziak JJ, Rudiger LP, Neale MC, et al. A twin study of inattentive, aggressive, and anxious/depressed behaviors. J Am Acad Child Adolesc Psychiatry in press.
Nadder TS, Silberg JL, Eaves LJ, et al. Genetic effects on ADHD symptomatology in 7- to 13-year-old twins: results from a telephone survey. Behav Genet 1998;28:83–99.
Rhee SH, Waldman ID, Hay DA, et al. Sex differences in ge- netic and environmental influences on DSM-III-R attention- deficit/hyperactivity disorder. J Abnorm Psychol 1999;108: 24–41.
Light JG, Pennington BF, Gilger J, et al. Reading disability and hyperactivity disorder: evidence for a common genetic etiology. Dev Neuropsychol 1995;11:323–335.
Stevenson J, Pennington BF, Gilger JW, et al. Hyperactivity and spelling disability: testing for shared genetic aetiology. J Child Psychol Psychiatry 1993;34:1137–1152.
Willicutt EG, Pennington BF, DeFries JC. A twin study of the etiology of comorbidity between reading disability and atten- tion-deficit/hyperactivity disorder. Am J Med Genet 2000;96: 293–301.
Silberg J, Rutter M, Meyer J, et al. Genetic and environmental influences on the covariation between hyperactivity and conduct disturbance in juvenile twins. J Child Psychol Psychiatry 1996; 37:803–816.
Halperin J, Sharma V, Siever L, et al. Serotonergic function in aggressive and nonaggressive boys with attention deficit hyper- activity disorder. Am J Psychiatry 1994;151:243–248.
Cantwell DP. Genetics of hyperactivity. J Child Psychol Psychia- try 1975;16:261–264.
Morrison JR, Stewart MA. The psychiatric status of the legal families of adopted hyperactive children. Arch Gen Psychiatry 1973;28:888–891.
Alberts-Corush J, Firestone P, Goodman JT. Attention and impulsivity characteristics of the biological and adoptive parents of hyperactive and normal control children. Am J Orthopsychia- try 1986;56:413–423.
Morrison JR, Stewart MA. Bilateral inheritance as evidence for polygenicity in the hyperactive child syndrome. J Nerv Ment Dis 1974;158:226–228.
Deutsch CK, Matthysse S, Swanson JM, et al. Genetic latent structure analysis of dysmorphology in attention deficit disor- der. J Am Acad Child Adolesc Psychiatry 1990;29:189–194.
Eaves L, Silberg J, Hewitt J, et al. Genes, personality, and psy- chopathology: a latent class analysis of liability to symptoms of attention-deficit hyperactivity disorder in twins. In: Plomin R, McLearn G, eds. Nature, Nurture and Psychology. Washington, DC: American Psychological Association, 1993:285–306.
Hess EJ, Rogan PK, Domoto M, et al. Absence of linkage of apparently single gene mediated ADHD with the human syn- tenic region of the mouse mutant coloboma. Am J Med Genet 1995;60:573–579.
Lopera F, Palacio LG, JimenezI, et al. Discrimination between genetic factors in attention deficit. Rev Neurol 1999;28: 660–664.
Chapter 43: Pathophysiology of ADHD
Maher BS, Marazita ML, Moss HB. Segregation analysis of attention deficit hyperactivity disorder. Am J Med Gen 1999; 88:71–78.
Hauser P, Zametkin A, MartinezP, et al. Attention deficit- hyperactivity disorder in people with generalized resistance to thyroid hormone. N Engl J Med 1993;328:997–1001.
Weiss R, Stein M, Trommer B, et al. Attention-deficit hyperac- tivity disorder and thyroid function. J Pediatr 1993;123: 539–545.
Weiss RE, Stein MA, Duck SC, et al. Low intelligence but not attention deficit hyperactivity disorder is associated with resistance to thyroid hormone caused by mutation R316H in the thyroid hormone receptor B gene. J Clin Endocrinol Metab 1994;78:1525–1528.
Barr CL, Wigg KG, Bloom S, et al. Further evidence from haplotype analysis for linkage of the dopamine D4 receptor gene and attention-deficit hyperactivity disorder. Am J Med Genet 2000;96:262–267.
Comings DE, Gonzalez N, Wu S, et al. Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compul- sive, addictive behaviors: Tourette syndrome, ADHD, patho- logical gambling, and substance abuse. Am J Med Genet 1999; 88:358–368.
Faraone SV, Biederman J, Weiffenbach B, et al. Dopamine D4 gene 7-repeat allele and attention deficit hyperactivity disorder. Am J Psychiatry 1999;156:768–770.
LaHoste GJ, Swanson JM, Wigal SB, et al. Dopamine D4 recep- tor gene polymorphism is associated with attention deficit hy- peractivity disorder. Mol Psychiatry 1996;1:121–124.
Rowe DC, Stever C, Giedinghagen LN, et al. Dopamine DRD4 receptor polymorphism and attention deficit hyperactivity dis- order [see Comments]. Mol Psychiatry 1998;3:419–426.
Smalley SL, Bailey JN, Palmer CG, et al. Evidence that the dopamine D4 receptor is a susceptibility gene in attention deficit hyperactivity disorder [see Comments]. Mol Psychiatry 1998;3: 427–430.
Swanson JM, Sunohara GA, Kennedy JL, et al. Association of the dopamine receptor D4 (DRD4) gene with a refined pheno- type of attention deficit hyperactivity disorder (ADHD): a fam- ily-based approach. Mol Psychiatry 1998;3:38–41.
Asherson P, Virdee V, Curran S, et al. Association of DSM-IV attention deficit hyperactivity disorder and monoamine path- way genes. Am J Med Genet 1998;81:548.
Castellanos FX, Lau E, Tayebi N, et al. Lack of an association between a dopamine-4 receptor polymorphism and attention- deficit/hyperactivity disorder: genetic and brain morphometric analyses [see Comments]. Mol Psychiatry 1998;3:431–434.
Daly G, Hawi Z, Fitzgerald M, et al. Attention deficit hyperac- tivity disorder: association with the dopamine transporter (DAT1) but not with the dopamine D4 receptor (DRD4). Am J Med Genet 1998;81:501.
Eisenberg J, Zohar A, Mei-Tal G, et al. A halotype relative risk study of the dopamine D4 receptor (DRD4) exon III repeat polymorphism and attention deficit hyperactivity disorder (ADHD). Am J Med Genet 2000;96:258–261.
Hawi Z, McCarron M, Kirley A, et al. No association of dopa- mine DRD4 receptor (DRD4) gene polymorphism in attention deficit hyperactivity disorder (ADHD) in the Irish population. Am J Med Genet 2000;96:268–272.
Asghari V, Sanyal S, Buchwaldt S, et al. Modulation of intracel- lular cyclic AMP levels by different human dopamine D4 recep- tor variants. J Neurochem 1995;65:1157–1165.
Ebstein RP, Novick O, Umansky R, et al. Dopamine D4 recep- tor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nat Genet 1996;12:78–80.
Benjamin J, Patterson C, Greenberg BD, et al. Population and