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SME Specific MeasuresQuality of Life and Management of Living Resources

Exploratory Award

Proposal number EXAW-1999-01412

AcronymCYPRALL

Proposal titleDEVELOPMENT OF STANDARDISED EXTRACT FOR DIAGNOSIS/THERAPY OF

CYPRESS POLLEN ALLERGY AND SELECTION OF LESS ALLERGENIC CYPRESS

PLANTS

AbstractAllergic diseases have been increasing in industrialized countries, affecting more than 20% of

European population. In particular pollen from Cupressus spp. plants, frequently used in

the pastyears in several reafforestation programs, is emerging as severe cause of pollinosis.

Unfortunatelythe lack of a standardised Cupressus pollen extract for diagnostic use as well

as its early period ofimpollination ( november -march) makes difficult an exact diagnosis,

mistaking allergic symptomsfor seasonal illness. Our research project purposes to reach

three main goals: a) to determine thedistribution of various Cupressus spp. throughout

Mediterranean Europe and their impact onpollinosis; b) to develop a standardised

Cupressus pollen extract for improving diagnosispossibilities and as a needed premise for

preparing a therapeutic vaccine; c) to select Cupressusspp. clones plants with low allergen

content and for low pollen production and/or restricted periodof impollination.

Key ActionQOL-4.   Key action Environment and Health

Start date20/11/2000End date20/11/2001

Intended Step 2 projectCooperative Research (CRAFT)Duration Exploratory Phase12 months

SME CoordinatorPRESIDENT RUBENS VAGLIOCompany sizeS4

LOFARMA S.P.A.

VIALE VASSALA 40

20143 - MILANO

Italy

Phone: 00392581981

Fax: 0039258198217

Email: LOFAMMI@MICRONET.IT

Internet: WWW.LOFARMA.IT

SME Proposer(s)

C.B.F. LETI, S.A.SpainS4

Profile of partners for joining the project

Business areas

CommentsWE NEED THE INVOLVEMENT AS INDUSTRIAL PARTNER OF A FIRM OPERATING

ASNURSERY PLANTS AND VARIOUS RESEARCH GROUPS WITH DIFFERENT

SCIENTIFICEXPERIENCE (BOTANICS, CHEMISTS, IMMUNOLOGISTICS) AND

ALLERGOLOGISTISFOR CLINICAL TRIALS.

Last update18/6/2001

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