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CTC NOTICE OF MODIFICATIONS

Grade

Adverse Event

  • 0

    1

2

CPK (creatine phosphokinase)

Hypercalcemia

Hypercholesterolemia

Hyperglycemia

Hyperkalemia Hypermagnesemia

Hypernatremia Hypertriglyceridemia Hyperuricemia

Also consider Tumor lysis... Hypocalcemia

The Also consider for Hyperuricemia was revised by replacing the word Potassium with Hyperkalemia.

Hypoglycemia

Hypokalemia Hypomagnesemia

Hyponatremia

Hypophosphatemia

Hypothyroidism is graded in... Lipase

Metabolic/Laboratory - Other (Specify, __________)

MUSCULOSKELETAL

Arthralgia is... Arthritis

Cancer Therapy Evaluation Program Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS March 1998

17

Version 2.0 Publish Date: April 30, 1999

3

4

The Grade 4 criteria for Hyperglycemia was revised to >500 mg/dL >27.8 mmol/L or acidosis (“ketoacidosis” was deleted).

Revised March 23, 1998

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