CTC NOTICE OF MODIFICATIONS
Version 2.0 Publish Date: April 30, 1999
Muscle weakness (not due to neuropathy)
Myalgia [tenderness or pain...
The grading instructions for Myalgia was revised to Myalgia [tenderness or pain in muscles] is graded in the PAIN category.
Myositis (inflammation/damage of muscle)
Also consider CPK. Note: Myositis implies...
Osteonecrosis (avascular necrosis)
Musculoskeletal – Other (Specify, __________)
Aphasia, receptive and/or...
Also consider Headache... Ataxia (incoordination)
CNS cerebrovascular ischemia
CNS hemorrhage/bleeding is graded...
Cognitive disturbance/ learning problems
Cancer Therapy Evaluation Program Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS March 1998
Revised March 23, 1998