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CTC NOTICE OF MODIFICATIONS

Grade

Adverse Event Confusion

0

1

2

3

Cranial neuropathy is graded in... Delusions

Depressed level of consciousness

Note: Syncope (fainting)... Dizziness/lightheadedness

Dysphasia, receptive and/or...

Extrapyramidal/ involuntary movement/ restlessness

Hallucinations Headache is graded in the PAIN... Insomnia

Note: This adverse event is…

G1

Irritability (children <3 years of age)

Leukoencephalopathy associated radiological findings

The italics and row shading were removed from the Leukoencephalopathy associated radiological findings event.

Memory loss

Cancer Therapy Evaluation Program Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS March 1998

19

Version 2.0 Publish Date: April 30, 1999

4

Revised March 23, 1998

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