CTC NOTICE OF MODIFICATIONS
Version 2.0 Publish Date: April 30, 1999
Adverse Event Inner ear/hearing
Auditory/Hearing - Other (Specify, __________)
Bone marrow cellularity
The Grade 1 value for Bone marrow cellularity was changed to mildly hypocellular or 25% reduction (“” was added).
Normal ranges: children ( 18 years)
The row listing normal ranges for children was shaded and the text changed to italic to indicate pediatric information.
younger adults (19-59)
older adults ( 60 years)
Note: Grade Bone... CD4 count Haptoglobin Hemoglobin (Hgb)
The value for Grade 3 Hemoglobin was changed to 65 - < 80 g/L (“<” was added).
For leukemia studies or bone marrow infiltrative/ myelophthisic processes, if specified in the protocol.
Hemolysis (e.g., immune hemolytic anemia, drug- related hemolysis, other)
Also consider Haptoglobin…
The abbreviation Hgb was written in full as Hemoglobin.
Cancer Therapy Evaluation Program Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS March 1998
Revised March 23, 1998