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CTC NOTICE OF MODIFICATIONS

Grade

Adverse Event

0

1

2

Ventricular arrhythmia (PVCs/bigeminy/trigeminy/ ventricular tachycardia)

Cardiovascular/ Arrhythmia - Other (Specify, ___________)

CARDIOVASCULAR (GENERAL)

Acute vascular leak syndrome

Cardiac-ischemia/infarction

Cardiac left ventricular function

CNS cerebrovascular ischemia is... Cardiac troponin I (cTnI)

Cardiac troponin T (cTnT) Edema

Hypertension

*Note: For pediatric patient...

Cancer Therapy Evaluation Program Common Toxicity Criteria, Version 2.0 DCTD, NCI, NIH, DHHS March 1998

5

3

Version 2.0 Publish Date: April 30, 1999

4

Revised March 23, 1998

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