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Asthma Health Outcomes Project

Overviews of Surveyed Asthma ProgramsSeptember 2005

Domestic Programs: North CarolinaBack to Index

ICAS: Inner-City Asthma Study

Rho Corporation, Data Coordinating Center

Chapel Hill, NC

Herman Mitchell, PhD

hmitchell@rhoworld.com

The Inner-City Asthma Study was conducted by the Inner-City Asthma Study Group, a collaboration of several institutions and investigators including NIAID and NIEHS as well as several universities, medical schools, and medical centers nationwide. The study was implemented in seven US cities: Tucson, AZ, Chicago, IL, Boston, MA, Bronx, NY, New York, NY, Dallas, TX, and Seattle, WA.

937 children with atopic asthma, aged 5-11 years, from all seven cities were enrolled in a randomized, controlled trial of an environmental intervention that lasted one year and included education and remediation for exposure to both allergens and environmental tobacco smoke. Home environmental exposures were assessed every six months, and asthma-related complications were assessed every two months during the intervention and for one year after the intervention.

The study concluded that among inner-city children with atopic asthma, an individualized, home-based, comprehensive environmental intervention decreases exposure to indoor allergens, including cockroach and dust-mite allergens, resulting in reduced asthma-associated morbidity.

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