Asthma Health Outcomes Project
Overviews of Surveyed Asthma ProgramsSeptember 2005
International Programs: The Netherlands
Clinical Effectiveness of a Mite Allergen-Impermeable Bed Covering System in Asthmatic Mite-Sensitive Patients
6500 HB Nijmegen The Netherlands
Lisette van den Bemt, MSc
The "Clinical Effectiveness of a Mite Allergen-Impermeable Bed-Covering System in Asthmatic Mite-Sensitive Patients" pilot study was implemented in 1998-1999. The objective was to measure the effect of house dust mite (HDM)- impermeable covers on HDM allergen levels, peak flow values, and asthma symptoms. A randomized clinical trial was carried out on asthma patients 12-60 years.
Fifty-two allergic asthmatic patients were randomly allocated to use the HDM-impermeable or placebo covers. During the study period, daily peak flow and asthma symptom scores were recorded. Dust samples were taken from the mattresses.
A significant reduction in HDM allergen levels on the mattresses after encasing them with HDM-impermeable covers was observed. Baseline symptoms were so low that no improvement could be established. Morning peak expiratory flow was significantly higher in the intervention group compared with that seen in the placebo group during the study period.
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