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Asthma Health Outcomes Project

Overviews of Surveyed Asthma ProgramsSeptember 2005

International Programs: The Netherlands (cont’d)Back to Index

Clinical Effects of Air Cleaners in Homes of Asthmatic Children Sensitized to Pet Allergens

University Hospital

9713 GZ Groningen The Netherlands

Sicco van der Heide, MS

The objective of the study, "Clinical Effects of Air Cleaners in Homes of Asthmatic Children Sensitized to Pet Allergens", was to investigate the clinical effects of air cleaners in living rooms and bedrooms of children with asthma sensitized to cat or dog allergens.

Twenty children with asthma sensitized to pet allergens (cat/dog) and with an animal at home participated in a double-blind, placebo-controlled, cross-over study in which the effects of air cleaners placed in the living room and bedroom for three months were compared with the effects of placebo air cleaners. Before and after each study period, lung function, airway hyper repsonsiveness, and peak flow variation were recorded. Cat and dog allergen levels were assessed in the filters of the air cleaners.

After a three-month intervention with active air cleaners, airway hyper rsponsiveness decreased significantly. Peak flow amplitude also significantly decreased. Substantial amounts of airborne cat and dog allergen were captured by the air cleaners in living rooms and bedrooms as well.

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