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Asthma Health Outcomes Project

Overviews of Surveyed Asthma ProgramsSeptember 2005

International Programs: United Kingdom Back to Index

The Respiratory Effects of Reduction of Mite Allergen in the Bedrooms of Asthmatic Children - A Double-Blind Controlled Trial

Institute of Child Health, Royal Hospital for Sick Children

BS2 8BJ United Kingdom

Dr. F. Carswell

The objective of the study was to investigate whether a double-blind randomized placebo-controlled community based study aimed at reducing the HDM allergens in the bedrooms of HDM sensitive asthmatic children using the best methods available would prove beneficial to the children's health. Seventy children aged 7-10 years in Bristol, United Kingdom were recruited based on criteria and then randomized to the active or placebo group. In the active group, the children's bedrooms were treated with an acaricide (Acarosan) and the mattresses, pillows and duvets were encased in exclusion covers. The control group received placebo treatments. Data was collected at baseline and 2, 6 and 24 weeks post treatment. The study period was 1992-1993.

Applying bedding covers and Acarosan led to a reduction in mite allergen on the mattress by 6 weeks. By 24 weeks, the active group had improved forced expiratory volume and fewer required bronchodilator therapy.

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