Canine severe eosinophlic dermatitis
Canine severe eosinophilic dermatitis characterized by acute eosinophilic dermatitis with vasculopathy / vasculitis and oedemaand has been described as a discrete syndrome in dogs. Recent retrospective studies have shown that many cases have followed treatment of severe gastrointestinal illness and it is proposed that the skin condition may have a causal drug association, possibly drug combination effects or perhaps due to a more generalized hypersensitivity response. Skin lesions usually develop within 7 days or sooner following institution of treatment with multiple drugs for GI disease. Cutaneous lesions are characterized by erythematous to hemorrhagic macule or plaques through to ulcerated nodules, distribution being predominantly on the ventral abdomen , flanks and limbs.