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Dr Rick Last Specialist Veterinary Pathologist - page 23 / 24

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RVF histopathology Bovine calves

  • -

    Multifocal random hepatic necrosis coalescing in some

areas to form zones of pan-necrosis (Image top right)

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    Fibrin deposition in sinusoids with haemorrhage and lytic

hepatocellular necrosis. Vasculitis is a well documented and common lesion in calves which is not commonly documented in adults or fetuses. Widespread fibrinocellular thrombosis in portal vein and hepatic sinusoids (Image bottom right).

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    Hepatocyte nuclear chromatin margination with multiple,

pale, eosinophilic, intra-nuclear inclusion bodies – arrows (Image below)

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