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Advancing MS RESEARCH

ORAL FUMARATE

Dr. Shubin and Neuro-Therapeutics are looking for men and women, aged 18-50 with RRMS to participate in a clinical trial of oral Fumarate or BG00012, which is also a pill study. To be eligible you need to be able to walk without a cane or walker and have had one relapse in the past year or two relapses in the past two years. To participate or learn more, please contact Donna Sider, RN at 626.356.0800.

MEMORY STUDY

Dr. Nancy Sicotte at UCLA is evaluating memory in MS using cognitive testing and MRI. Researchers need men and women with relapsing MS as well as people who do not have MS to participate. There is payment for participation. If interested, please call Mike Montag at 310.825.7313 for a 15-minute phone screening to determine if you qualify.

PHASE II ESTRIOL TRIAL

Dr. Rhonda Voskuhl and researchers at UCLA are looking for women with RRMS for a 24- month study to see if there are less relapses with the treatment of Copaxone injections plus oral estriol as compared to the treatment of Copaxone plus oral placebo.

You may be eligible if you are 18-50 years old, diagnosed with RRMS, able to walk unassisted, and have had at least one relapse within the last 2 years. You are not eligible if you have ever received Copaxone or have been treated with Avonex, Rebif or Betaseron for more than 3 months. If interested, call Mike Montag at 310.825.7313 for info and a 20-minute phone screening to determine initial eligibility.

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National M

ONCE-DAILY ORAL FTY720

Investigators nationwide are enrolling for a phase 3 clinical trial evaluating the safety and effectiveness of a once-a-day pill called fingolimod (also known as FTY720, by Novartis Pharmaceuticals Corp.) compared to placebo in people with relapsing-remitting MS (RRMS).

Participants in the 24-month study must be 18-55 years old with RRMS, with at least one documented relapse during the previous year or two relapses during the previous two years. For more info, please see the study Web site at www.msclinicaltrials.com. To participate at Cedars Sinai, please contact Leslie Tarlow, NP at leslie.tarlow@cshs.org or 310.423.3457.

LOKOMAT STUDY

Dr. Barbara Giesser and colleagues at UCLA are testing a new rehabilitation approach to improve walking ability in people with MS, using a robotic device that moves the legs while the person is suspended over a treadmill. People with progressive forms of MS will undergo 36 training sessions over 12 weeks. Half will receive robotic locomotor training and half standard resistive exercise training.

If you are 18-60 years old, diagnosed with definite PPMS or SPMS and have difficulty walking, you may be eligible. You are not eligible if you are unable to use an assistive device such as a walker. If interested, please call Elise Herlihy, RN at 310.267.4071 for info.

To view a complete list of clinical trials currently recruiting patients with MS in California, please visit www.nationalMSsociety.org/clinicaltrials.

ultiple Sclerosis Society, Southern California Chapter

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