VZV can cross the placenta in the late stages of pregnancy to infect the fetus congenitally.
Neonatal varicella may vary from a mild disease to a fatal disseminated infection.
If rash in mother occurs more than 1 week before delivery, then sufficient immunity would have been transferred to the fetus.
Zoster immunoglobulin should be given to susceptible pregnant women who had contact with suspected cases of varicella.
Zoster immunoglobulin should also be given to infants whose mothers develop varicella during the last 7 days of pregnancy or the first 14 days after delivery.