Clinical Manifestations (1)
Primary HHV-6 infection is associated with Roseala Infantum, which is a classical disease of childhood.
Most cases occur in infants between the ages of 4 months and two years.
A spiking fever develops over a period of 2 days followed by a mild rash. The fever is high enough to cause febrile convulsions.
There are reports that the disease may be complicated by encephalitis.