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XDR and MDR and TB Urgent Research Priorities - page 2 / 24

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TB Drug resistance

Worldwide surveillance indicates substantial and rising rates and numbers of M.TB  resistant to existing medications

Multiple drug resistant  MDR-TB

~ 400,000 cases of MDR-TB a year

10,000 MDR patients under treatment in GLC programs

Global goal – treat 800,000 MDR cases by 2015

Highest rates in Former Soviet Union and China

Limited information from Africa

Well known association of outbreaks with HIV co-infection in industrialized world

Relationship between TB drug resistance and HIV not

well defined

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