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XDR and MDR and TB Urgent Research Priorities - page 23 / 24

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Majority of patients infected with the same KZN strain

Databases 1994 to 2005 searched for resistance patterns in isolates of M.TB with KZN strain fingerprint.

In 1994, KZN strain cases with MDR TB, with some STM resistance

From 1994, MDR isolates found with resistance to additional drugs

First XDR isolate in 2001

Resistance to up to 7 drugs developed in a decade.

Evolution of the extensive drug resistant (XDR) KZN strain of M.TB in KwaZulu-Natal

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