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XDR and MDR and TB Urgent Research Priorities - page 24 / 24

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Coincided with:

High TB prevalence and weak TB control program

Explosive HIV epidemic

Dramatic TB increase and overwhelming of TB services

Introduction of the DOTS based TB control program

Standardized treatment in absence of drug susceptibility    testing or resistance surveillance

Adding of single drug to failing regimen-STM

Widespread antibiotic use for non-TB disease

Evolution of the extensive drug resistant (XDR) KZN strain of M. tuberculosis in KwaZulu-Natal

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