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Immunity and Diseases Scientific background to autoimmune diseases - page 13 / 22

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Reasons put forward so far includes;

Differences in Antibody production

Females produces more Ab than males

They also mount more vigorous immune response than males

Sex hormones also play important role

Studies have shown that estrogen can stimulate auto-antibody production

Demonstrated in SLE-prone mice

Testosterone seems to be protective against several types of autoimmune diseases, eg.SLE, diabetes,MS etc

Ability of pregnant women to modify their immune system during pregnancy to keep the fetus

The presence of fetal cell in maternal circulation for decades – this can also lead to the development of autoimmune diseases  

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